Mesolift

There are various "anti-ageing" treatments available to meet the growing demand of patients. Management of skin ageing should be considered as an overall process involving a variety of complementary techniques.

Indications will depend on various factors such as the area to be treated, stage of ageing and skin type.

Mesolift is part of the overall management process.

This technique combined with hyaluronic acid-based solutions can compensate poor quality or loss of endogenous hyaluronic acid. Injected into the dermal-epidermal junction or the superficial dermis, exogenous hyaluronic acid rapidly reaches the dermis. This has the following results :

• Recolonisation of the extracellular matrix
• Improved skin hydration and elasticity
• Disappearance of fine lines resulting in dazzlingly beautiful skin.

This treatment is therefore particularly recommended for :

• patients who smoke
• patients with "tired" skin
• patients who have undergone dermabrasion
• patients exposed to sunlight for long periods of time
• post partum patients
  
   

  Before Juvelift	After Juvelift

Advantages of Juvelift

Juvelift is a solution of non cross-linked hyaluronic acid of biosynthetic origin, designed for mesolift techniques applied to the face, neck, décolleté and back of the hands.

13.5mg/g concentration of hyaluronic acid, i.e. a concentration 1,000 times higher than that of the endogenous hyaluronic acid concentration in the epidermis (15 ug/g) and 200 times higher than that in the dermis (740 ug/g) to the power of 15.
Molecular weight of 2.5.10 to the power of 6 Da (the highest on the market), at least double that of the skin (10 to the power of 6 Da).

The ratio of molecular weight (2.5.10 to the power of 6 Da) / percentage of hyaluronic acid (1.35 %) in Juvelift guarantees the strengthening of the molecular network and thus allows:

• increase in its water-holding capacity
• building a protective screen against the free radicals responsible for damage.

The high molecular weight and concentration of Juvelift provide more active and longer lasting hydration to prevent and combat skin ageing. Skin tonicity is enhanced.

Endogenous hyaluronic acid in dehydrated dermis.	Action of Juvelift.

Treatment

The choice of therapeutic protocol will depend on the stage of ageing, the patient's wishes and their budget. Several sessions may be required to achieve the desired effect. This will involve the practitioner drawing up an injection schedule for each individual patient.

A minimum interval of two weeks should be observed between sessions.

This treatment may be supplemented by injection of Juvederm wrinkle fillers.

Injection techniques

Juvelift can be injected into areas of the face, neck, décolleté and hands whose skin has lost its tonicity and reveals fine lines.

Serial puncture technique

This technique is possible manually or with an injection gun. It consists of micro injections into the dermal-epidermal junction or the superficial dermis of the face, neck, décolleté or the back of the hands.

Patients must be warned that the effects of "papular" serial puncture injections may still be visible 2 or 3 days after the session, depending on skin type.

Linear threading or cross-hatching technique

This technique is mainly used on lines in fragile areas of the face caused by facial expressions: crow's feet, smile lines on the cheeks and oral commissars. In this case, Juvelift corneal, is injected into the superficial dermis using the linear threading technique, by means of either plain linear injections or vertical injections followed by horizontal ones (cross-hatching).

Tolerance

Hyaluronic acid is already used in a variety of therapeutic indications such as ophthalmology, rheumatology and dentistry. In dermatology, it is used as a healing adjuvant and filler for skin depressions.

Its pharmacological properties, distribution and metabolism profiles and the risks associated with product use have given rise to numerous studies and are well known and described in the literature.

Clinical risks for the patient are related to the product used and not hyaluronic acid itself.

These are :

• Biocompatibility
• Microbiological safety
• pH and osmolarity

Juvelift prevents these risks through :

• its choice of hyaluronic acid which
   
  • is the result of bacterial fermentation (from Streptococcus equi)
  • meets the requirements of the European Pharmacopoeia 4th ed.
  • has been rated as being free of BSE risk by the European Commission
  • has been used in other indications for 8 years.
    
     
• its formulation and manufacturing process which benefit from the expertise and experience of CORNEAL®, one of the world's few laboratories to master production of hyaluronic acid-based solutions. This guarantees a solution which :
   
  • is sterile (SAL < 10 to the power of 6 compliant with the requirements of European standard EN 556-A1 for sterile MDs)
  • is non-pyrogenic
  • has a pH (6,7-7,8) and osmolarity (approx. 320 mOsm) compatible with its use.
  • is biocompatible according to the requirements of international standard ISO 10993-1 (non-irritating, non-sensitising, non-cytotoxic, free of systemic toxicity, non-genotoxic, free of tissue reaction)

Contra indications and side effects

The "contra-indications and side-effects" are described in the Juvelift instruction leaflet. These are of the same type as those identified for all injectable Medical Devices used in the treatment and prevention of skin ageing.

Nevertheless, if side-effects persist beyond a week or if any other side-effect should occur, the patient should inform the doctor without delay so that appropriate curative treatment can be administered.

Technical datas